Making antibiotic development great again: has the code been cracked for narrow-spectrum agents?

Once in a while you see an idea that is both so brilliant and so obvious that you just have to smack your head and ask “Why has no one thought of this before? Why didn’t I think of it?”. There’s a general consensus that broad-spectrum antibiotics are over-used. The consequences are many and egregious: Read More …

An apocalypse or just a disaster?

A new report of widespread colonization and infection by a superbug- (carbapenemase-resistant Klebsiella) is just out, and it is truly alarming. Not sure why it hasn’t cracked the mainstream press yet. I don’t have access to the full report, but Jon Otter has published a good summary which I will quote here, although you absolutely should Read More …