Why has genomics been so unsuccessful in the discovery of new medicines?

NB – this question was first posted on Quora in 2010 The fact that this question is as relevant in 2019 as it was in 2010 tells us something, does it not? I think we can throw out the “we just need more time” plea. Francis Collins, leader of the human genome initiative and now Read More …

Mutations with benefits – resisting epidemics.

The term “mutation” is a bit loaded, as it implies a defect or deficiency or aberration of some sort. But the value of a particular version of a gene is very much dependent on its context – what might be a defect in one context conveys an advantage in another. And that context means not Read More …