Why has genomics been so unsuccessful in the discovery of new medicines?

NB – this question was first posted on Quora in 2010 The fact that this question is as relevant in 2019 as it was in 2010 tells us something, does it not? I think we can throw out the “we just need more time” plea. Francis Collins, leader of the human genome initiative and now Read More …

Will gene therapies ultimately become more prevalent than traditional drugs?

It is hard to imagine how this could happen. Let’s assume that all the technical obstacles that now plague gene therapy[1] are resolved. In other words, that we learn how to deliver genes efficiently to the appropriate tissues without any side effects. Gene therapy would still be appropriate for only a tiny fraction of human Read More …