How does CancerSEEK compare to other liquid biopsies?

This work[1] blows away previous efforts. The word “breakthrough” is used far too often to describe results that are incremental, or that are promising but not well-supported. CancerSEEK is a genuine breakthrough. The gold standard for cancer diagnosis is the biopsy – a bit of suspect tissue is excised and studied, and determined to be benign Read More …

What is the promise of gene editing?

For society as a whole, not much. One of the unexpected findings of genomics is just how little our genomes matter to disease – particularly for chronic illnesses like heart disease and cancer. Not only are genetic contributions small compared to environmental ones, but their influence is spread out over dozens of genes. Fixing any one of Read More …

The emperor’s new speedos

There’s no doubt that the emergence of genomics was a huge scientific breakthrough. It supercharged research in any number of disciplines, and essentially created new ones such as microbiomics. But it hasn’t done the one thing it was supposed to do: transform the diagnosis and treatment of disease. The first genome was sequenced in 2001. Many Read More …