Do coffee, garlic, or hot peppers kill friendly gut bacteria?

The short answer is no. Although nearly all plants contain antimicrobial compounds, these compounds are present only at low concentrations. Diet certainly influences microbiome composition. But this influence works through the availability of foods that different bacteria prefer. “Food antibiotics” are not a thing. Sloppy health journalists are responsible for the confusion. They often call Read More …

Is virus evolution making vaccine development more difficult?

From Quora: Viruses have not evolved to become “resistant” to vaccines the way that bacteria have evolved to become resistant to antibiotics. Vaccines don’t attack viruses directly, they just prime our immune systems to do so. Our immune systems and viruses have been battling it out for hundreds of millions of years, and the likelihood Read More …

Antimicrobial resistance is not humanity’s greatest threat

It’s not unusual to see headlines like this in health journalism: Antibiotic Resistance Is Now as Big a Threat as Climate Change To be fair, the article itself is not nearly so hysterical; in fact it doesn’t even mention climate change. Yet some editor thinks that this nonsense is an appropriate way to summarize the Read More …

Making antibiotic development great again: has the code been cracked for narrow-spectrum agents?

Once in a while you see an idea that is both so brilliant and so obvious that you just have to smack your head and ask “Why has no one thought of this before? Why didn’t I think of it?”. There’s a general consensus that broad-spectrum antibiotics are over-used. The consequences are many and egregious: Read More …

Why aren’t all those breakthroughs translating into cures?

One of the ways that science journalism continually fails the public is by ignoring the Valley of Death that lies between discovery and product development. The problem is especially acute in healthcare, where the maddening complexity and unpredictability of clinical responses dooms most “breakthroughs” to failure. The problem is less ignorance on the part of Read More …

Sorry, but taking blood samples is not colonialism

Today’s sci journo fail is a bonus entry – it is also a history fail. The title, “COLONIALISTS ARE COMING FOR BLOOD—LITERALLY” pretty well sums up the argument: taking blood samples for therapeutic and diagnostic development purposes is exactly the same as stealing diamonds, gold, timber, arable land and people from poorer countries. Please. Blood Read More …

Potential phage therapy applications: Pseudomonas lung infections in cystic fibrosis patients

Phage therapy isn’t ever going to be the cure-all envisioned by overly-enthusiastic science writers. But it doesn’t have to be. Curing some patients of some indications is a noble and worthy goal in and of itself. And maybe when we learn to use phage therapy in limited applications, we can start thinking about tackling sepsis Read More …