Do coffee, garlic, or hot peppers kill friendly gut bacteria?

The short answer is no. Although nearly all plants contain antimicrobial compounds, these compounds are present only at low concentrations. Diet certainly influences microbiome composition. But this influence works through the availability of foods that different bacteria prefer. “Food antibiotics” are not a thing. Sloppy health journalists are responsible for the confusion. They often call Read More …

Is there still room for amateurs in science?

Until the end of the 19th century, nearly all science was done by amateurs. The first modern research university was Johns Hopkins, founded in 1876. Up until that time, universities were vehicles for transmitting established knowledge – divinely revealed wisdom at first, the humanistic classics later. They were not seen as engines for creating and Read More …

Is virus evolution making vaccine development more difficult?

From Quora: Viruses have not evolved to become “resistant” to vaccines the way that bacteria have evolved to become resistant to antibiotics. Vaccines don’t attack viruses directly, they just prime our immune systems to do so. Our immune systems and viruses have been battling it out for hundreds of millions of years, and the likelihood Read More …

Antimicrobial resistance is not humanity’s greatest threat

It’s not unusual to see headlines like this in health journalism: Antibiotic Resistance Is Now as Big a Threat as Climate Change To be fair, the article itself is not nearly so hysterical; in fact it doesn’t even mention climate change. Yet some editor thinks that this nonsense is an appropriate way to summarize the Read More …

Aptamers: still looking for euphoria in the wrong places

I admit to doing a spit-take when I saw the title of this article: Aptamers as Therapeutic Agents: Has the Initial Euphoria Subsided?. At this stage in the game, with only one aptamer therapeutic cleared and it having perennially weak sales, that question mark in the title seems more than a bit out of date. Read More …